IDT publications

Peer-reviewed articles published by IDT scientists. Filter using one or more categories to focus on specific topics.

159 Citations found

Walk RM, Elliot ST, Blanco FC, Snyder JA, Jacobi AM, Rose SD, Behlke MA, Salem AK, Vukmanovic S, Sandler AD. (2012) T-cell activation is enhanced by targeting IL-10 cytokine production in toll-like receptor- stimulated macrophages. ImmunoTargets and Therapy, 1 : 13–23.
Sakurai K, Amarzguioui M, Kim DH, Alluin J, Heale B, Song MS, Gatignol A, Behlke MA, Rossi JJ. (2011) A role for human Dicer in pre-RISC loading of siRNAs. Nucleic Acids Res, 39 : 1510–1525.
Devor EJ, Huang L, Wise A, Peek AS, Samallow PB. (2011) An X chromosome microRNA cluster in the marsupial species Monodelphis domestica. J Hered, 102 : 577–583.
Gantier MP, McCoy CE, Rusinova I, Saulep D, Wang D, Xu D, Irving AT, Behlke MA, Hertzoq PJ, Mackay F, Williams BR. (2011) Analysis of microRNA turnover in mammalian cells following Dicer1 ablation. Nucleic Acids Res, 39 : 5692–5703.
Lennox KA, Behlke MA. (2011) Chemical modification and design of anti-miRNA oligonucleotides. Gene Ther, 18 : 1111–1120.
You Y, Tataurov AV, Owczarzy R. (2011) Measuring thermodynamic details of DNA hybridization using fluorescence. Biopolymers, 95 : 472–486.
Melkman-Zehavi T, Oren R, Kredo-Russo S, Shapira T, Mandelbaum AD, Rivkin N, Nir T, Lennox KA, Behlke MA, Dor Y, Hornstein E. (2011) miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressor. EMBO J, 30 : 835–845.
Thiel WH, Bair T, Wyatt-Thiel K, Dassie, JP, Rockey WM, Howell CA, Liu XY, Dupuy AJ, Huang L, Owczarzy R, Behlke MA, McNamara JO, Giangrande PH. (2011) Nucleotide bias observed with a short SELEX RNA aptamer library. Nucleic Acid Ther, 21 : 253–263.
Dobosy JR, Rose SD, Beltz KR, Rupp SM, Powers KM, Behlke MA, Walder JA. (2011) RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers. BMC Biotechnol, 11 : 1–18.
Michel CI, Holley CL, Scruggs BS, Sidhu R, Brookheart RT, Listenberger LL, Behlke MA, Ory DS, Schaffer JE. (2011) Small nucleolar RNAs U32a, U33, and U35a are critical mediators of metabolic stress. Cell Metab, 14 : 33–44.
Owczarzy R, You Y, Groth CL, Tataurov AV. (2011) Stability and mismatch discrimination of locked nucleic acid-DNA duplexes. Biochem, 50 : 9352–9367.

New nearest-neighbor parameters correctly forecast the positive and negative effects of LNAs on mismatch discrimination. Specificity is enhanced in a majority of sequences and is dependent on mismatch type and adjacent base pairs.

Rockey WM, Huang L, Kloepping KC, Baumhover NJ, Giangrande PH, Schultz MK. (2011) Synthesis and radiolabeling of chelator-RNA aptamer bioconjugates with copper-64 for targeted molecular imaging. Bioorg Med Chem, 19 : 4080–4090.
Lennox KA, Behlke MA. (2010) A direct comparison of anti-microRNA oligonucleotide potency. Pharm. Res, 27 : 1788–1799.
Ge Q, Dallas A, Ilves H, Shorenstein J, Behlke MA, Johnston BH. (2010) Effects of chemical modifications on the potency, serum stability, and immunostimulatory properties of short shRNAs. RNA, 16 : 118–130.
Gantier MP, Irving AT, Kaparakis-Liaskos M, Xu D, Evans VA, Cameron PU, Bourne JA, Ferrero RL, John M, Behlke MA, Williams BR. (2010) Genetic modulation of TLR8 response following bacterial phagocytosis. Hum Mutat, 31 : 1069–1079.
Nawroth I, Alsner J, Behlke MA, Besenbacher F, Overgaard J, Howard KA, Kjems J. (2010) Intraperitoneal administration of chitosan/DsiRNA nanoparticles targeting TNFa prevents radiation-induced fibrosis. Radiother Oncol, 97 : 143–148.
Chen AK, Davydenko O, Behlke MA, Tsourkas A. (2010) Ratiometric bimolecular beacons for the sensitive detection of RNA in single living cells. Nucleic Acids Res, 38 : e148.
Gantier MP, Tong S, Behlke MA, Irving AT, Lappas M, Nilsson UW, Latz E, McMillan NA, Williams BR. (2010) Rational design of immunostimulatory siRNAs. Mol Ther, 18 : 785–795.
Monteys AM, Spengler RM, Wan J, Tecedor L, Lennox KA, Xing Y, Davidson BL. (2010) Structure and activity of putative intronic miRNA promoters. RNA, 16 : 495–505.
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