IDT publications

Peer-reviewed articles published by IDT scientists. Filter using one or more categories to focus on specific topics.

169 Citations found

Lennox KA, Behlke, MA. (2016) Mini-review on current strategies to knockdown long non-coding RNAs. J Rare Dis Res Treat , 1 : 66–70.
Zhao D, Yang Y, Qu N, Chen M, Ma Z, Krueger CJ, Behlke MA, Chen AK. (2016) Single-molecule detection and tracking of RNA transcripts in living cells using phosphorothioate-optimized 2′-O-methyl RNA molecular beacons. Biomaterials, 100 : 172–183.
Ramachandran S, Osterhaus SR, Parekh KR, Jacobi AM, Behlke MA, McCray PB Jr. (2016) SYVN1, NEDD8, and FBXO2 regulate δ508-CFTR ubiquitin-mediated proteasomal degradation. J Biol Chem, 291 : 25489–25504.
Pauli A, Montague TG, Lennox KA, Behlke MA, Schier AF. (2015) Antisense oligonucleotide-mediated transcript knockdown in Zebrafish. PLoS One, 10 : e0139504.
Khan SM, Min A, Gora S, Houranieh GM, Campden R, Robitaille M, Trieu P, Petrin D, Jacobi AM, Behlke MA, Angers S, Hebert TE. (2015) Gb4g1 as a modulator of M3 muscarinic receptor signaling and novel roles of Gb1 subunits in the modulation of cellular signaling. Cell Signal, 27 : 1597–1608.
Ezzat K, Aoki Y, Koo T, McClorey G, Benner L, Coenen-Stass A, O’Donovan L, Lehto T, Garcia-Guerra A, Nordin J, Saleh AF, Behlke M, Morris J, Goyenvalle A, Dugovic B, Leumann C, Gordon S, Gait MJ, El Andaloussi S, Wood MJ. (2015) Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides. Nano lett, 15 : 4364–4373.
Sarvestani ST, Stunden HJ, Behlke MA, Forster SC, McCoy CE, Tate MD, Ferrand J, Lennox KA, Latz E, Williams BRG, Gantier MP.. (2015) Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors. Nucl Acid Res, 43 : 1177–1188.
Khairuddin N, Blake SJ, Firdaus F, Steptoe RJ, Behlke MA, Hertzog PJ, McMillan NA. (2014) In vivo comparison of local versus systemic delivery of immunostimulating siRNA in HPV-driven tumours. Immunol Cell Biol, 92 : 156–163.
Hammond SM, McClorey G, Nordin JZ, Godfrey C, Stenler S, Lennox KA, Smith CE, Jacobi AM, Varela MA, Lee Y, Behlke MA, Wood MJ, Andaloussi SE. (2014) Correlating in vitro splice switching activity with systemic in vivo delivery using novel ZEN-modified oligonucleotides. Mol Ther Nucl Acids, 3 : e212.
Zhang X, Zajac AL, Huang L, Behlke MA, Tsourkas A. (2014) Imaging the directed transport of single engineered RNA transcripts in real-time using ratiometric bimolecular beacons. PLoS One, 9 : e85813.
Sarvestani ST, Tate MD, Moffat, JM, Jacobi AM, Behlke, MA, Miller AR, Beckham SA, McCoy CE, Chen W, Mintern JD, O’Keeffe M, John M, Williams BR, Gantier MP. (2014) Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8. J Virol, 88 : 799–810.
Dudek H, Wong DH, Arvan R, Shah A, Wortham K, Ying B, Diwanji R, Zhou W, Holmes B, Yang H, Cyr WA, Zhou Y, Shah A, Farkiwala R, Lee M, Li Y, Rettig GR, Collingwood MA, Basu SK, Behlke MA, Brown BD. (2014) Knockdown of β-catenin with Dicer-substrate siRNAs reduces liver tumor burden in vivo. Mol Ther, 22 : 92–101.
Hernandez FJ, Huang L, Olson ME, Power KM, Hernandez LI, Meyerholz DK, Thedens DR, Behlke MA, Horswill AR, JcNamara JO 2nd. (2014) Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe. Nat Med, 20 : 301–306.
Krishnamurthy S, Behlke MA, Apicella MA, McCray PB, Davidson BL. (2014) Platelet activating factor receptor activation improves siRNA uptake and RNAi responses in well-differentiated airway epithelia. Mol Ther Nucl Acids, 3 : e175.
Song Y, Zhang X, Huang L, Behlke MA, Tsourkas A. (2014) Real-time imaging of single engineered RNA transcripts in living cells using ratiometric bimolecular beacons. J Vis Exp, 90 : e51544.
Bestas B, Moreno PM, Blomberg KE, Mohammad DK, Sutlu T, Nordin JA, Guterstam P, Gustafsson MO, Kharazi S, Piatosa B, Roberts TC, Behlke MA, Wood MJ, Gait MJ, Lundin, KE, El Andaloussi S, Mansson R, Berglof A, Wengel J, Smith CI. (2014) Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model. J Clin Invest, 124 : 4067–4081.
Cheng C, Chen YH, Lennox KA, Behlke MA, Davidson BL. (2013) In vivo SELEX for identification of brain-penetrating aptamers. Mol Ther Nucleic Acids, 8 : e67.
Rodriguez-Lebron E, Liu G, Keiser M, Behlke MA, Davidson BL. (2013) Altered Purkinje cell miRNA expression and SCA1 pathogenesis. Neurobiol Dis, 54 : 456–463.
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